CORDIS · PROCRYSTAL
Crystallisation towards efficient and sustainable biomanufacturing
- Code
PROCRYSTAL- Programme
- HORIZON
- Call
- MSCA Doctoral Networks 2023
HORIZON-MSCA-2023-DN-01-01 - Status
- SIGNED
- Period
- 2025-01-01 – 2028-12-31
Official data · CORDIS · synced 2026-10-18 03:29 · official record
Participants
| Organisations | Role | Country | Grant |
|---|---|---|---|
| UNIVERSIDADE DO MINHO | coordinator | PT | 730 210 € |
| CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS | participant | FR | 565 387 € |
| AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS | participant | ES | 503 942 € |
| SECOYA TECHNOLOGIES | participant | BE | 262 620 € |
| JANSSEN PHARMACEUTICA NV | participant | BE | 262 620 € |
| VRIJE UNIVERSITEIT BRUSSEL | participant | BE | 262 620 € |
| KATHOLIEKE UNIVERSITEIT LEUVEN | participant | BE | 262 620 € |
| BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM | participant | HU | 228 348 € |
| ХИМИКО-ТЕХНОЛОГИЧЕН И МЕТАЛУРГИЧЕН УНИВЕРСИТЕТ | participant | BG | 207 295 € |
| Lamark Biotech SAS | associated partner | FR | |
| EOS SRL | associated partner | IT | |
| UNIVERSITE D'AIX MARSEILLE | associated partner | FR | |
| UNIVERSIDADE NOVA DE LISBOA | associated partner | PT | |
| MOLECULAR DIMENSIONS LIMITED | associated partner | UK | |
| SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT | associated partner | FR | |
| UNIVERSIDAD DE GRANADA | associated partner | ES | |
| IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE | associated partner | UK |
Description
Downstream processing (DSP) of biopharmaceuticals is dominated by chromatographic steps which suffer from low throughput, poor scalability and elevated energy consumption, as well as high equipment and materials costs. To this is added the low stability and high degradability of liquid formulations. The training program ""Crystallisation towards efficient and sustainable biomanufacturing"" (PROCRYSTAL) vision is that of crystallisation as a simple, sustainable, cost-efficient and scalable alternative to current DSP techniques and liquid formulations, once it allows to separate, purify and stabilise in a single step. Nevertheless, integrated training to exploit biocrystallisation full potential is currently not available, only fragmented research activities. Within this training program, 13 Doctoral candidates (DCs) are expected to go beyond current practise to respond to the near future biopharma manufacturing needs. And only possible leveraged by the expertise conveyed in this consortium on biomolecules crystallisation, biochemistry, chemical and process engineering as well as advanced modelling. The PROCRYSTAL training program for the DCs has been framed with special attention to fundamental understanding of the underlying phenomena, from the molecular scale to process scale, and advanced experimental and modelling techniques specific to crystallisation technology. The DCs will acquire a wide range of subject specific and general transferable skills, in an interdisciplinary and inter-sectoral environment and by multinational collaboration which enhances the early-career DCs long term employability and competitiveness.""
Official data · CORDIS · synced 2026-10-18 03:29 · official record · Licence: © European Union, CC BY 4.0 (Commission reuse policy).