CORDIS · HypoSens
Nano-confined photonic system for detection of breast cancer spread to the lymph nodes
- Code
HypoSens- Programme
- H2020
- Call
ICT-29-2016- Status
- CLOSED
- Period
- 2016-11-01 – 2019-10-31
Official data · CORDIS · synced 2026-10-17 10:16 · official record
Participants
| Organisations | Role | Country | Grant |
|---|---|---|---|
| ACONDICIONAMIENTO TARRASENSE ASSOCIACION | coordinator | ES | 672 084 € |
| TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY | participant | IL | 539 041 € |
| MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV | participant | DE | 490 981 € |
| FUNDACION RIOJA SALUD-FRS | participant | ES | 407 678 € |
| SOFIA UNIVERSITY ST KLIMENT OHRIDSKI | participant | BG | 403 162 € |
| BCB Informatica y Control S.L. | participant | ES | 372 500 € |
| OBELIS SA | participant | BE | 319 200 € |
| FUNDACION FUNDITEC | participant | ES | 276 449 € |
| KNOWLEDGE INNOVATION MARKET SL | participant | ES | 240 250 € |
| UFO | participant | AL | 193 750 € |
| INSPIRALIA SOCIEDAD LIMITADA | participant | ES | 83 551 € |
Description
The Vision of HypoSens is to develop a widely accepted,non-invasive and crucial prognostic tool for breast cancer progression in early stages to help clinicians and specially oncologists to decide about prompt therapy approaches to patients and improve quality of life and expectancy. Our breakthrough research will focus on the development, pre-clinical and clinical validation, and industrial demonstration of a unique all optical cancer prognostic system that will determine presence of cancer cells in the breast lymph nodes and characterize them, which correlates with presence of metastasis and bad prognosis. HypoSens prognostic system will consist of a non-invasive Near-infrared imaging device able to register signals through scattering media enabled by the implementation of wavefront shaping,that will process data collected by injected tumour-targeted body antibody functionalised nano-particles containing porphyrin sensors that will determine local oxygen concentration and local temperature distribution in the cancer cells.The HypoSens imaging system is strategically designed to offer a non-invasive alternative to the Sentinel Lymph Node Biopsy,the current surgical procedure for breast cancer staging. With an approximate cost of 60,000€ per device unit and additional 5,000€ per patient, the device is an affordable, accurate, easy to use prognostic solution for clinicians towards more accurate and fast diagnostics and personalised treatment options.The initial target of the project is metastatic breast cancer, with potential later involvement in other cancer markets, e.g. vulval, renal, colorectal, gastric etc (via the use of different tumor-targeting moiety).With an estimated 1.7 million new cases each year, breast cancer is the most common cancer among women worldwide.Its low cost will enable a wide and fast take-up by clinicians and hospitals leading to an important reduction of the economic and societal burden related to the diagnosis and treatment of cancer.
Official data · CORDIS · synced 2026-10-17 10:16 · official record · Licence: © European Union, CC BY 4.0 (Commission reuse policy).