CORDIS · MET-EFFECT
Metal complexes of a naturally inspired framework functionalized for cytotoxic and catalytic efficiency
- Code
MET-EFFECT- Programme
- HORIZON
- Call
HORIZON-MSCA-2021-SE-01-01- Status
- SIGNED
- Period
- 2023-01-01 – 2026-12-31
Official data · CORDIS · synced 2026-10-17 10:16 · official record
Participants
| Organisations | Role | Country | Grant |
|---|---|---|---|
| Innovative Centre Faculty of Chemistry Belgrade LTD | coordinator | RS | 170 200 € |
| VENUSROUZES LABSOLUTIONS | participant | BG | 216 200 € |
| IST-ID ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E O DESENVOLVIMENTO | participant | PT | 128 800 € |
| CENTIV GMBH | participant | DE | 124 200 € |
| UNIVERSITAET GRAZ | participant | AT | 124 200 € |
| CASE WESTERN RESERVE UNIVERSITY CORPORATION | associated partner | US |
Description
The immense power of practice-oriented synthetic chemistry is demonstrated through the opportunity to design, synthesize, optimize, produce and apply a molecule of a desirable structure for a given purpose. In the light of its ability to bridge chemical structure with a function, MET-EFFECT proposes brand new concept of novel multifunctional rhenium and iridium flavonoid complexes aimed to serve as metallodrugs and homogenous catalysts. The fusion of academic knowledge and industry-oriented perspective establishes a fruitful collaboration of an international and intersectoral profile. Well-recognized members of Consortium gains beyond the-state-of-the-art advances in bioinorganic chemistry by: a) developing novel Re and Ir complexes containing apigenin-like ligands, a natural bioactive flavone-type of molecules; b) determining the antitumor potential of newly synthesized Re(V) and Ir(III) complexes on a panel of various human cancer cell lines; c) evaluating the applicative potential of novel Re(V) complexes as homogeneous catalysts in OAT-inspired reactions (olefin epoxidation, oxoanions catalytic reduction and water oxidation). The structure and sentence of 7 work packages implemented through 37 secondments will enable the promotion of newly synthesized metal-based compounds in industrial environment for the sake of reaching their final applications. The widespread partnership creates an outstanding, R&I oriented ambient ensuring free knowledge sharing and career upgrade of the participating staff. By developing functional metal-based molecules, MET-EFFECT encompasses full human intellectual capacity capable to challenge technical, economic and environmental demands of wider society for applied but sustainable chemistry.
Official data · CORDIS · synced 2026-10-17 10:16 · official record · Licence: © European Union, CC BY 4.0 (Commission reuse policy).